Our Mission

Sarcopenia, characterized by the loss of skeletal muscle mass and function, is a common complication in patients with liver cirrhosis.
It can lead to reduced physical strength, impaired mobility, and increased risk of falls and hospitalizations.
Our mission is to reach out to every sarcopenic patient with liver cirrhosis and provide them with the necessary support and resources to improve their health and quality of life.

Prevalence and Burden of
Liver Diseases in India

Our Mission: Is to serve each sarcopenic patient with complete nutritional care & support. Every patient should receive the finest nutritional care possible in order to optimize their liver health and overall wellbeing. Together with raising awareness about sarcopenia in liver cirrhosis, we are dedicated to offer each patient the best nutritional care along with complete liver care assistance.

Our Vision: Our Vision is to be the leading provider for nutritional support in the management of Liver diseases, and to excel in patient care and nutritional management.

Sarcopenia in Liver Cirrhosis: Sarcopenia is a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength with a risk of adverse outcomes such as frailty, falls, fractures, physical disability, poor quality of life and death. The main symptom of the condition is muscle weakness.

Sarcopenia is a prevalent muscle abnormality in patients with cirrhosis that confers poor prognosis both pre- and post-liver transplantation. The prevalence of sarcopenia in patients with cirrhosis ranges from 40 to 70%. The pathogenesis of sarcopenia is multifactorial and results from an imbalance between protein synthesis and breakdown.

A combination of nutritional, physical, and pharmacological interventions might be necessary to reverse sarcopenia in cirrhosis. Moderate exercise should be combined with appropriate energy and protein intake, in accordance with clinical guidelines. - J Gastroenterol 2019 Oct; 54(10):845-859

Prevalence and Burden of Liver Cirrhosis

With a high frequency and severe disease burden, liver cirrhosis is a serious public health issue in India. The burden of liver disease in India is significant because it alone contributed to 18.3% of the two million global liver disease–related deaths in 2015.

Contribution of cirrhosis and its complications, collectively chronic liver diseases (CLDs), as causes of mortality in India have been increasing progressively.

Overall, NAFLD and ALD are emerging as important causes of CLD in the country paralleling the changes in lifestyle and social customs.

Different CLDs and cirrhosis accounted for 2.1% of all deaths in India.

The burden of liver cirrhosis in India is particularly high due to the high prevalence of risk factors such as viral hepatitis, alcohol consumption, and non-alcoholic fatty liver disease (NAFLD).- Clin Liver Dis (Hoboken). 2022 Mar; 19(3): 114–117

Management of Sarcopenia

Physical Exercise
  • Aerobic Exercise
  • Resistance Execrise
Hormone Therapy
  • Testosterone Supplement
  • Ghrelin Supplement
  • GH Supplement
Rational Nutrition
  • Protein and Vitamin D
  • Mediterranean Diet
  • ACEI and ARB Drugs
  • Loop Diuretics
Pronocte Pro Book
The Science Behind Pronocte Protein Powder
May 25, 2024
Regaining Strength: How Pronocte Can Help Manage Sarcopenia in Liver Cirrhosis

Living with liver cirrhosis presents a daily set of challenges. This chronic condition affects liver function, impacting various bodily processes, including protein synthesis. One significant consequence of this can be sarcopenia, a gradual loss of muscle mass and strength.

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Unveiling the benefits of Nocturnal Protein Supplementation.
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Nighttime Advantage: Unveiling the Benefits of Nocturnal Protein Supplementation

The quest for optimal muscle health and recovery is a constant pursuit for athletes, fitness enthusiasts, and anyone concerned with maintaining strength and mobility as they age. Traditional protein shakes consumed throughout the day have long been a staple in this pursuit. However, recent research suggests a new frontier – the potential benefits of nocturnal protein supplementation.

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Pronocte Protein Powder stands out in the crowded market of protein supplements due to its unique scientific formulation. At the core of its effectiveness lies the carefully chosen combination of whey protein isolate, whey protein concentrate, and casein protein. Understanding the science behind these ingredients sheds light on how Pronocte promotes muscle tissue growth and repair.

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Together, we can make a difference in the lives of sarcopenic patients with liver cirrhosis by promoting early detection, implementing effective interventions, and fostering a supportive environment for their well-being.